Certified Pharmacy Technician (CPhT) Practice Exam

Certified Pharmacy Technician (CPhT)

About Certified Pharmacy Technician (CPhT)

Certified Pharmacy Technician (CPhT) is the foundation of a rewarding career as a pharmacy technician. The certification is an important first step toward a rewarding career in healthcare. As a CPhT, you can work effectively to support your pharmacy team and provide superior patient care.

Prerequisite for the exam

• Completion of a PTCB-Recognized Education/Training Program or equivalent work experience
• Full disclosure of all criminal and State Board of Pharmacy registration or licensure actions
• Compliance with all applicable PTCB Certification policies
• Passing score on the Pharmacy Technician Certification Exam

Exam Structure

1. Domain 1: Medications (40%)

• Generic names, brand names, and classifications of medications 

• Therapeutic equivalence

• Common and life-threatening drug interactions and contraindications (e.g., drug-disease, drug-drug, drug-dietary supplement, drug-laboratory, drug-nutrient)

• Strengths/dose, dosage forms, routes of administration, special handling and administration instructions, and duration of drug therapy

• Common and severe medication side effects, adverse effects, and allergies

• Indications of medications and dietary supplements

• Drug stability (e.g., oral suspensions, insulin, reconstitutables, injectables, vaccinations)

• Narrow therapeutic index (NTI) medications

• Physical and chemical incompatibilities related to non-sterile compounding and reconstitution 

• Proper storage of medications (e.g., temperature ranges, light sensitivity, restricted access)

2. Domain 2: Federal Requirements (12.5%)

• Federal requirements for handling and disposal of non-hazardous, hazardous, and pharmaceutical substances and waste

• Federal requirements for controlled substance prescriptions (i.e., new, refill, transfer) and DEA controlled substance schedules

• Federal requirements (e.g., DEA, FDA) for controlled substances (i.e., receiving, storing, ordering, labeling, dispensing, reverse distribution, take-back programs, and loss or theft of)

• Federal requirements for restricted drug programs and related medication processing (e.g., pseudoephedrine, Risk Evaluation and Mitigation Strategies [REMS])

• FDA recall requirements (e.g., medications, devices, supplies, supplements, classifications)

3. Domain 3: Patient Safety and Quality Assurance (26.25%)

• High-alert/risk medications and look-alike/sound-alike [LASA] medications

• Error prevention strategies (e.g., prescription or medication order to correct patient, Tall Man lettering, separating inventory, leading and trailing zeros, bar code usage, limit use of error-prone abbreviations)

• Issues that require pharmacist intervention (e.g., drug utilization review [DUR], adverse drug event [ADE], OTC recommendation, therapeutic substitution, misuse, adherence, post-immunization follow-up, allergies, drug interactions)

• Event reporting procedures (e.g., medication errors, adverse effects, and product integrity, MedWatch, near miss, root-cause analysis [RCA])

• Types of prescription errors (e.g., abnormal doses, early refill, incorrect quantity, incorrect patient, incorrect drug)

• Hygiene and cleaning standards (e.g., handwashing, personal protective equipment [PPE], cleaning counting trays, countertop, and equipment)

4. Domain 4: Order Entry and Processing (21.25%) 

• Procedures to compound non-sterile products (e.g., ointments, mixtures, liquids, emulsions, suppositories, enemas)

• Formulas, calculations, ratios, proportions, alligations, conversions, Sig codes (e.g., b.i.d.k, t.i.d., Roman numerals), abbreviations, medical terminology, and symbols for days supply, quantity, dose, concentration, dilutions

• Equipment/supplies required for drug administration (e.g., package size, unit dose, diabetic supplies, spacers, oral and injectable syringes)

• Lot numbers, expiration dates, and National Drug Code (NDC) numbers

• Procedures for identifying and returning dispensable, non-dispensable, and expired medications and supplies (e.g., credit return, return to stock, reverse distribution)

Exam Pattern

• Exam Name: Certified Pharmacy Technician (CPhT)
• Length of Time: 2 Hours

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